Persufflation—Current State of Play

Inflammometry: the current state of play.

It is now 20 years since the late Freddy Hargreave and colleagues developed a valid, safe and feasible technique to assess airway inflammation using induced sputum. At around the same time Kjell Alving and colleagues reported that the concentration of exhaled nitric oxide (FENO) is raised in patients with asthma. There has since been huge research interest in these techniques over the last 20 y...

The Quantum Measurement Problem: State of Play

This is a preliminary version of an article to appear in the forthcoming Ashgate Companion to the New Philosophy of Physics. In it, I aim to review, in a way accessible to foundationally interested physicists as well as physics-informed philosophers, just where we have got to in the quest for a solution to the measurement problem. I don’t advocate any particular approach to the measurement prob...

Wastewater Irrigation : the State of Play

As competition among industrial, agricultural, urban and environmental sectors for freshwater intensifies, wastewater is frequently being seen as a valuable resource rather than mere waste. Furthermore, wise reuse of this water alleviates environmental concerns attendant with its discharge to coastal environments and inland waterways. Globally, around 20 million ha of land are irrigated with wa...

Report on the current state of play

The state-of-play and future of platinum drugs.

The year 2015 marks the 50th anniversary since the discovery of the anticancer potential of cisplatin and it remains just as useful now as it did back then, especially for the treatment of some endocrine-related cancers like ovarian and testicular carcinomas. Since its discovery, five other platin drugs have received approval in various countries. While several new platin drugs are in preclinic...